具有两种免疫来源的乙肝病毒模型的全局动力学
Global Dynamics of an HBV Model with Two Immune Response Sources
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摘要: 研究了免疫反应具有两种来源的乙肝病毒模型.通过对相应特征方程的分析,讨论了感染平衡态和未感染平衡态的局部稳定性,证明了基本再生数>1时疾病的持续性.通过几何方法的应用,得到了感染平衡点全局稳定性的充分条件.Abstract: In this paper,an HBV model with activated immune response of two sources is studied.By analyzing the corresponding characteristic equations,the local stability of an infected steady state and an uninfected steady state is discussed.It is proved that if the basic reproductive number is more than one,the disease is persistent.By applying a geometric method,sufficient conditions are obtained for the global stability of the endemic equilibrium.
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