复方苦芩总黄酮对免疫抑制小鼠免疫功能的影响
- 西南大学 荣昌校区 兽医科学研究中心中药创新研究室,重庆荣昌,402460
摘要: 为了观察复方苦芩总黄酮对免疫抑制小鼠的免疫增强作用，用环磷酰胺构建小鼠免疫抑制模型，给免疫抑制小鼠灌服复方苦芩总黄酮，检测碳粒廓清指数，脾脏指数，胸腺指数，血清溶血素水平及 T，B淋巴细胞转化率．结果显示：复方苦芩总黄酮能够提高免疫抑制小鼠的碳粒廓清指数、脾脏指数、胸腺指数，同时也能够提高小鼠血清溶血素水平和增强T ，B淋巴细胞转化率，与模型组比较差异极具有统计学意义（p＜0.01），且高剂量和中剂量组效果优于低剂量组，差异具有统计学意义（p＜0.05）或者极具有统计学意义（p＜0.01）．表明复方苦芩总黄酮能增强机体的免疫功能．
Effect of the Total Flavonoids in Kuqin Compound on Immune Function of Immunosuppressed Mice
- 西南大学 荣昌校区 兽医科学研究中心中药创新研究室,重庆荣昌,402460
Abstract: In order to study the effects of the total flavonoids in Kuqin compound on immunosuppressed mice .The model of immune suppression in mice was induced by cyclophosphamide and the immunosup‐pressed mice were fed by the total flavonoids in Kuqin compound ,then detected the carbon clearance in‐dex ,the spleen index ,the thymus index ,the serum hemolysim and the T ,B lymphocyte proliferation rate in immunosuppressed mice .The results showed that the total flavonoids in Kuqin compound could in‐creased the carbon clearance index ,the immune organ index ,the serum hemolysim and enhanced the T ,B lymphocyte proliferation rate in immunosuppressed mice .The difference was significant compared with model group (p < 0.01) ,and the effect of high‐dose group ,mid‐dose group were better the low‐dose group ,appeared difference (p<0.05) or significant difference (p<0.01) .Therefore the total flavonoids in Kuqin compound could increase the body's immune function .
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